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Notes
      3. Pharmacology
          3.1. Pharmacology principles
              3.1.2. Pharmacodynamics
                  3.1.2.2. Mechanism of drug actions
                      3.1.2.2.1. Receptors
 3.1.2.2.1.3. Receptor occupancy theory

Receptor occupancy theory

[Ref: SH4:p22]

Traditionally...

  • The intensity of effect of a drug is proportional to the fraction of receptors occupied by the durg.
    --> Maximal drug effect occurs when all receptors are occupied.
  • Flaw: Does not account for antagonist or partial agonist.
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Receptor_occupancy_theory.html
Part of study notes by LD99
Revised at 02/11/2007 23:37
Version 2