Topics
Today's topic
Chp 21 Histamine
Chp 24 Insulin
Chp 25 Diuretics
Chp 27 Anticoagulants
Chp 28 Antimicrobials
Chp 32 Lipid disorder
Chp 33 CNS stimulants and muscle relaxants
Chp 36 Bloods
The BIG FIVE
- Inhaled anaesthetics
- Intravenous anaesthetics
* Barbiturates
* Benzodiazepines
* Nonbarbiturate IV anaesthetics
- Local anaesthetics
- Analgesia
* Opioids
* NSAIDs
- Muscle-relaxants
* Also reversals (anticholinesterase)
Other important topics
CVS drugs
* Sympathomimetics
* Digitalis and others
* Adrenoreceptor antagonists
* Antihypertensive drugs
* Anti-arrhythmics
* Vasodilators
Antiemetics
Diuretics
Anti-microbials
Drugs affecting coagulation
Hypoglycaemic agents
Corticosteroids and other hormone preparations
Drugs acting on the GIT
CNS drugs
Phase I vs Phase II block
Topics skipped (needs to go back to)
Chp 19 Psych drugs
Chp 20 Prostaglandins
Chp 22 Serotonin
Chp 23 Hormones
Chp 26 Antacids and GIT drugs
Chp 29 Chemotherapeutic
Chp 30 Antiepileptic drugs
Chp 31 Parkinson's drug
Chp 34 Vitamins
Chp 35 Minerals and electrolytes
Chp 37 Enteral and parenteral nutrition
Chp 38 Antiseptics and disinfectants
Topics to make flash cards on
Droperidol
Haloperidol
Clonidine
Inhaled anaesthetics
- ISO
- SEVO
- DES
- HAL
- ENF
- METH
- N2O
Intravenous anaesthetics
Barbiturates
- Thiopentone
- ??? Methohexital
- ??? Phenobarbital
- ???
Benzodiazepines
- Midazolam
- Diazepam
- Flumazenil
Non-barbiturate IV anaesthetic drugs
- Propofol
- Ketamine
- Etomidate
Local anaesthetics
Ester
Amide
Analgesia
Opioid
- Morphine
- Fentanyl
- Sufentanil
- Alfentanil
- Remifentanil
- Methadone
- Tramadol
- Codeine
- Pethidine
- Naloxone
- Heroin
Muscle-relaxants
Adrenoreceptor antagonists
- Propanolol
- Esmolol
- Metoprolol
- Atenolol
- Timolol
- Labetalol
- Prazosin
- Clonidine
- Dexmedetomidine
Drug information to note
For every drug, I need to know
Classification
Pharmaceutical information
Formulation/preparation
Price
pH of preparation
Preservatives
Solvent
Administration/Route
Dosage
pK
Pharmacodynamics
Mechanism of action
* e.g. receptors of action
Receptor and cellular level
Organ system (CVS, CNS, Resp, GIT, genitourinary, maternal/foetal, uterus, cutaneous, placenta
Pharmacokinetics
- Absorption
* Route of administration
* Speed
* Bioavailability
- Distribution
* Onset of action
* Effect-site equilibration time
* Redistribution
* Vd
* Protein-binding
- Metabolism
* Hepatic and extrahepatic metabolism
* Metabolite, active/inactive
*
- Excretion
* Duration of action
* Half-time (context-sensitive, elimination)
* Clearance (hepatic and renal)
* Impact of cirrhosis and renal failure
Clinical information
Adverse effects
- Side-effect
- Drug interaction
